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Could breast cancer survivors have A lower risk of Alzheimer’s disease?
South Korean researchers say Breast cancer survivors Have a risk of 8% of 8% of development of the condition compared to people without cancer, despite current concerns concerning cognitive decline after treatment.
“We found a slightly lower risk of [Alzheimer’s] Among breast cancer survivors, in accordance with several previous studies and a meta-analysis, ”wrote the authors in a study published Friday in the journal Jama Network OpenThe Open-Access Journal of the American Medical Association.
“This suggests that standard breast cancer treatments, including radiotherapy, may not increase and may even reduce the risk of short -term Alzheimer’s dementia,” said Dre Jeong of the National University of Seoul, who directed the study, said In the. “Clinicians can use this evidence to reassure patients with breast cancer concerned with their cognitive health.”
The researchers also found no association between the risk of Alzheimer’s and treatment with chemotherapeutic agents.
“An increased risk of dementia in patients with head and neck cancer treated with radiotherapy has been noted. However, the risk of MA could differ, depending on the dose of influence and the exhibition site, “they explained.
To achieve these conclusions, they examined the data of more than 70,000 patients who underwent breast cancer surgery between the first day in January 2010 and the last day of December 2016. The data was collected by the National Health Insurance Korean Service. The participants were grouped with healthy witnesses to age one to three report. Women underwent an average follow -up of 7.3 years.
Among the participants, 1,229 cases of Alzheimer’s were detected. Breast cancer survivors have shown a slightly lower risk of developing Alzheimer’s disease compared to women without cancer. The trend was particularly applicable to women aged 65 and over.
“However, historical analyzes have found that this lower risk does not persist beyond five years of survival. The treatment of radiotherapy cancer was associated with a reduced risk of [Alzheimer’s] Among the survivors, ”they wrote.
They say that additional research is necessary to assess the long -term risk of Alzheimer’s disease in breast cancer survivors.
Previous research of researchers from the University of Pittsburgh also revealed that the modulating hormone therapy used for the treatment of breast cancer was associated A 7% risk of development of Alzheimer’s disease and the dementias related later in life, and that Some women may be more at risk than others.
South Korean researchers have noted that cytotoxic chemotherapy has been recognized as a cause of cognitive decline called chemobrain in cancer survivors, referring to the problems of reflection and memory after treatment. The researchers added that their results suggest that this treatment does not lead directly to Alzheimer’s disease.
“The results suggest that certain cancer treatments potentially have advantages for the risk of lower Alzheimer’s disease”, the authors said.
